磷酸化肽基脯氨酞順反異構(gòu)酶Pinl抗體

Name: 磷酸化肽基脯氨酞順反異構(gòu)酶Pinl抗體bs-25159R
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簡(jiǎn)要描述：Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly res